There are two different playable races in Huxley: alternatives and sapiens. Alternatives were created when a mysterious material known as nuclearites caused "allopatric speciation" of the human race. Unaffected humans became known as sapiens, while affected humans are alternatives. As time went on, the human evolution path was once again interfered with by fragments of the moon, known as lunarites. The sapiens were divided into the factions One and Syn, and the alternatives were divided into the factions Alteraver and Alternix.Momenteel staat er nog geen releasedatum vast voor deze op de Unreal Engine 3 gebasseerde game. Wel is de kans groot dat de PC versie eerder uit zal komen dan de Xbox 360 versie. De PC versie zal bovendien te spelen zijn op de E3 beurs van komende maand.